Daily Shaarli
February 17, 2022
Analyses of both COVID-19 convalescent and diagnostic cohorts strongly support the use of RBD antibody levels as an excellent surrogate to biochemical neutralization activities. Data further revealed that the samples from mRNA vaccinated individuals had a median of 17 times higher RBD antibody levels and a similar degree of increased neutralization activities against RBD-ACE2 binding than those from natural infections. Our data showed that N501Y RBD had fivefold higher ACE2 binding than the original variant. While some antisera from naturally infected subjects had substantially reduced neutralization ability against N501Y RBD, all blood samples from vaccinated individuals were highly effective in neutralizing it. Thus, our data indicates that mRNA vaccination may generate more neutralizing RBD antibodies than natural immunity. It further suggests a potential need to maintain high RBD antibody levels to control the more infectious SARS-CoV-2 variants. //
Received
25 June 2021
Accepted
17 January 2022
Published
16 February 2022
The "BioNTainer" is a rather bland looking modular structure, but scientists here say two of these beige, two-storey containers could churn out up to 50 million doses of vaccine a year.
BioNTech intends to provide the containers, raw materials and know-how at no cost.
In return the host country would provide the land and, ensure that local infrastructure such as water and electricity is sufficient and reliable, and find people to work in the container.
So-called "filling and finishing" of the product would also happen in Africa.
The vaccines produced would be for use in the country where it was made or exported to other members of the African Union at a not-for-profit price.
"It's not cheap, we're talking millions" says BioNTech's Chief Operating Officer Sierk Poetting. "We're financing this at our own risk. We've developed this at our own risk. It's our goal to bring this to Africa."
Mark Twain Quotations, Newspaper Collections, & Related Resources
Directory of Mark Twain's maxims, quotations, and various opinions:
We spent a day with Ridley Scott et al in Toronto to hear how the film came to be.
Guess the WORLDLE in 6 guesses.
Each guess must be a valid country, territory, ...
After each guess, you will have the distance, the direction and the proximity from your guess and the target country.
A new WORLDLE will be available every day!
About distance
The distances displayed correspond to the distances between the selected and the target territory centers.
For instance, the computed distance between United States and Canada is around 2260km even if they have a common border.
The jurors “had involuntarily received ‘push notifications’ on their smartphones that contained the bottom-line of the ruling”. //
What the hay are jurors doing with ANY devices during trial proceedings??!!
Set up.