The airline reported the aircraft carried 84 tons of cargo from Seoul (South Korea) to Vienna (Austria) with a technical stop in Novosibirsk, where the aircraft after departure to Vienna performed an emergency return. The crew was taken to a local hospital as a precaution, no injuries occurred. A support team was dispatched to Novosibirsk with all needed equipment to assess the damage and move the aircraft off the runway.

In a videotaped interview the captain of the flight reported that the #2 engine (inboard left) blew up at about 1000 feet AGL (300 meters above ground) just after gear retraction with flaps still extended for takeoff, debris damaged the aircraft's cabling and took out all electrical supply resulting in the loss of all eletrical systems including instruments, brakes, thrust reversers etc. The aircraft remained controllable despite all electricity gone and all communication, even intercom having failed, lost. The crew attempted to establish visual contact with tower, however, without success, and proceeded to land on runway 25 with very little margin due to low altitude and engine thrust. After a smooth touchdown the overrun was unavoidable due to the loss of brakes, spoilers, thrust reversers.

On Nov 17th 2020 Rosaviatsia reported the aircraft carried 6 flight crew and 8 other crew as well as 83.5 tons of freight. As result of the destruction of the #2 engine in flight the aircraft sustained damage disabling the continuation of the flight and disallowing the possibility to stop the aircraft on the runway after landing. The aircraft overran the runway by about 300 meters/1000 feet resulting in the destruction of gear structures. Numerous holes punched through the fuselage damaged the structural integrity, the structural integry of the landing gear was compromised, numerous holes were punched into elements of the wings as well as the engine pylon. The crew reported the failure of the #2 engine caused the loss of braking, loss of power supply of the aircraft, loss of radio communications as well as limitations in the engine control. The gear was extended manually, the right hand nose gear did not extend (only the left hand nose gear and main gear struts extended).

According to Mode-S and ADS-B data the aircraft departed runway 25, climbed out, began turning right, reached 1825 feet MSL before the signal disappeared about 3.5nm past the runway end.